Resources 
Descriptions and links to our preferred resources:
AmiGO 2
AmiGO 2 is a project to create the next generation of AmiGO–the current official web-based set of tools for searching and browsing the Gene Ontology database.
bioRxiv
bioRxiv (pronounced “bio-archive”) is a free online archive and distribution service for unpublished preprints in the life sciences. It is operated by Cold Spring Harbor Laboratory, a not-for-profit research and educational institution. By posting preprints on bioRxiv, authors are able to make their findings immediately available to the scientific community and receive feedback on draft manuscripts before they are submitted to journals.
ChEMBL
ChEMBL is a manually curated database of bioactive molecules with drug-like properties. It brings together chemical, bioactivity and genomic data to aid the translation of genomic information into effective new drugs.
CyVerse
CyVerse provides life scientists with powerful computational infrastructure to handle huge datasets and complex analyses, thus enabling data-driven discovery. Our extensible platforms provide data storage, bioinformatics tools, image analyses, cloud services, APIs, and more.
HaploReg
HaploReg is a tool for exploring annotations of the noncoding genome at variants on haplotype blocks, such as candidate regulatory SNPs at disease-associated loci. Using LD information from the 1000 Genomes Project, linked SNPs and small indels can be visualized along with chromatin state and protein binding annotation from the Roadmap Epigenomics and ENCODE projects, sequence conservation across mammals, the effect of SNPs on regulatory motifs, and the effect of SNPs on expression from eQTL studies. HaploReg is designed for researchers developing mechanistic hypotheses of the impact of non-coding variants on clinical phenotypes and normal variation.
Inxight
The National Center for Advancing Translational Sciences (NCATS) has developed Inxight: Drugs as a comprehensive portal for drug development information. NCATS Inxight: Drugs contains information on ingredients in medicinal products, including:
- US APPROVED DRUGS: 2,351
- MARKETED DRUGS: 6,041
- INVESTIGATIONAL DRUGS: 7,099
- ALL SUBSTANCES: 107,353
NCATS Inxight: Drugs incorporates and unifies a wealth of data, including manually curated data supplied by the FDA and private companies, and provides marketing and regulatory status, rigorous drug ingredient definitions, biological activity, clinical use, and more.
LocusZoom
LocusZoom is a suite of tools to provide fast visualization of GWAS results for research and publication.
NCBI
The National Center for Biotechnology Information advances science and health by providing access to biomedical and genomic information.
Open Targets
Open Targets is an innovative, large-scale, multi-year, public-private partnership that uses human genetics and genomics data for systematic drug target identification and prioritisation.
Visit the Open Targets Platform which integrates public domain data to enable target identification and prioritisation, or the Open Targets Genetics Portal which identifies targets based on GWAS and functional genomics.
Oxford BIG
The primary aim of the browser is to support interpretation of Genome Wide Association Studies (GWAS) results for Brain Imaging phenotypes and possible links to GWAS of other non-brain imaging phenotypes. The browser is built on top of data from several sources.
Pharos
Pharos is the user interface to the Knowledge Management Center (KMC) for the Illuminating the Druggable Genome (IDG) program funded by the National Institutes of Health (NIH) Common Fund. (Grant No. 1U24CA224370-01). The goal of KMC is to develop a comprehensive, integrated knowledge-base for the Druggable Genome (DG) to illuminate the uncharacterized and/or poorly annotated portion of the DG, focusing on three of the most commonly drug-targeted protein families:
- G-protein-coupled receptors (GPCRs)
- ion channels (ICs)
- kinases
The Pharos interface provides facile access to all data types collected by the KMC. Given the complexity of the data surrounding any target, efficient and intuitive visualization has been a high priority, to enable users to quickly navigate & summarize search results and rapidly identify patterns. A critical feature of the interface is the ability to perform flexible search and subsequent drill down of search results. Underlying the interface is a RESTful API that provides programmatic access to all KMC data, allowing for easy consumption in user applications.
